Characters played by David Nowlin
Sam Sameth (segment "The Tomb of Sammun-Mak")
Characters played by William Kasten
Max Obediah Moleman (segments "The Penal Zone" - "They stole Max's brain") Radio Announcer (segments "The Penal Zone" - "They stole Max's brain" - "Beyond the Alley of the Dolls") Maximus (segment "The Tomb of Sammun-Mak") Jürgen (segments "The Tomb of Sammun-Mak" - "The City that dares not sleep") Maimtron (segment "The City that dares not sleep") (as William Kasten)
Characters played by Andrew Chaikin
Narrator Gordon the alien brain (segment "The Penal Zone") Jebediah Moleman (segments "The Penal Zone" - "They stole Max's brain") Anton Paperwaite (segments "The Tomb of Sammun-Mak" - "They stole Max's brain" - "Beyond the Alley of the Dolls" - "The City that dares not sleep") Guardian #1 (segment "The Tomb of Sammun-Mak") (as Andrew Chaikin) (as Kid Beyond)
Characters played by Roger Jackson
General Skun-ka'pe Grandpa Stinky (segments "The Penal Zone" - "They stole Max's brain" - "Beyond the Alley of the Dolls" - "The City that dares not sleep") Guardian #2 (segment "The Tomb of Sammun-Mak") Mole Grandpa (segment "The Tomb of Sammun-Mak") Ex Skun-ka'pe Minion (segment "They stole Max's brain") Charlie Ho-Tep (segment "Beyond the Alley of the Dolls") Abraham Lincoln (segment "The City that dares not sleep") Beelzebub (segment "The City that dares not sleep") (as Roger L. Jackson) (as Roger Jackson)
Characters played by Melissa Hutchison
Stinky (segments "The Penal Zone" - "They stole Max's brain" - "Beyond the Alley of the Dolls" - "The City that dares not sleep") Computer (segments "The Penal Zone" - "The City that dares not sleep") Rat #2 (segment "They stole Max's brain") Statue of Liberty (segment "Beyond the Alley of the Dolls")
Characters played by Peter Barto
Agent Superball (segments "The Penal Zone" - "Beyond the Alley of the Dolls" - "The City that dares not sleep") Flint Paper (segments "The Penal Zone" - "They stole Max's brain" - "Beyond the Alley of the Dolls" - "The City that dares not sleep") Skun-ka'pe Minion (segments "The Penal Zone" - "They stole Max's brain") Rat #3 (segment "They stole Max's brain") Peepers (segment "The City that dares not sleep")
Characters played by Cathleen Riddley
Doctor Momma Bosco (segments "The Penal Zone" - "Beyond the Alley of the Dolls" - "The City that dares not sleep")
Characters played by Tim Talbot
Harry Moleman (segments "The Penal Zone" - "Beyond the Alley of the Dolls") Construction Woker Moleman (segment "The Penal Zone") Mole Dad (segment "The Tomb of Sammun-Mak")
Characters played by Jared Emerson-Johnson
Skun-ka'pe Minion (segment "The Penal Zone") Curt 286 (segments "The Penal Zone" - "They stole Max's brain" - "The City that dares not sleep") Bob Bell (segments "The Penal Zone" - "They stole Max's brain" - "The City that dares not sleep") Bluster Blaster (segment "Beyond the Alley of the Dolls")
Characters played by Julian Kwasneski
Max's Psychic Wheel Skun-ka'pe Minion (segment "They stole Max's brain") Junior (segment "Beyond the Alley of the Dolls")
Characters played by Thessaly Lerner
Baby Amelia Earhart (segment "The Tomb of Sammun-Mak")
Characters played by Ruby Butterfield
Newsie the elf (segment "The Tomb of Sammun-Mak") Skun-ka'pe Minion (segments "They stole Max's brain" - "The City that dares not sleep")
Characters played by Terence McGovern
Nicholas St. Kringle (segment "The Tomb of Sammun-Mak") Snowcone the elf (segment "The Tomb of Sammun-Mak")
Characters played by Milissa Carey
Frostie the elf (segment "The Tomb of Sammun-Mak') Mole Woman (segment 'The Tomb of Sammun-Mak")
Characters played by Doug Boyd
Slushie the elf (segment "The Tomb of Sammun-Mak") Train Conductor (segment "The Tomb of Sammun-Mak")
Characters played by Rebecca Schweitzer
Mole Girl (segment "The Tomb of Sammun-Mak" - "They stole Max's brain" - "The City that dares not sleep")
Characters played by Brian Sommer
Frankie the rat (segment "They stole Max's brain")
Characters played by Vegas J. Jenkins
Sal (segments "They stole Max's brain" - "Beyond the Alley of the Dolls" - "The City that dares not sleep") (as Vegas Trip)
Characters played by Marius Fietzek Winter
Tourist (segment "They stole Max's brain") (as Majus Fietzek)
Characters played by Chuck Kourouklis
Dr. Norrington (segments "They stole Max's brain" - "Beyond the Alley of the Dolls" - "The City that dares not sleep")
Characters played by Rudy Muldoon
Troy, the Cthonic Destroy (segment "Beyond the Alley of the Dolls")
Characters played by Amy Provenzano
Sybil Pandemik (segment "The City that dares not sleep")
Characters played by David Boyll
Mr. Featherly (segment "The City that dares not sleep")
Characters played by Nikki Rapp
Sammun-Mak (segments "They stole Max's brain" - "The City that dares not sleep") Sam Jr. (segment "The City that dares not sleep") (as Nicki Rapp)