Characters played by Patrick Dempsey
Tom
Characters played by Michelle Monaghan
Hannah
Characters played by Kevin McKidd
Colin
Characters played by Kadeem Hardison
Felix
Characters played by Chris Messina
Dennis
Characters played by Richmond Arquette
Gary
Characters played by Busy Philipps
Melissa
Characters played by Whitney Cummings
Stephanie
Characters played by Emily Nelson
Hilary
Characters played by Kathleen Quinlan
Joan
Characters played by Selma Stern
Grandma Pearl
Characters played by Sydney Pollack
Thomas Sr.
Characters played by James Sikking
Reverend Foote
Characters played by Kevin Sussman
Tiny Shorts Guy
Characters played by Beau Garrett
Gloria