Characters played by Robert Guillaume
Dr. Eli Vance
Characters played by Robert Culp
Dr. Wallace Breen
Characters played by Louis Gossett Jr.
Vortigaunt
Characters played by Michelle Forbes
Dr. Judith Mossman
Characters played by Merle Dandridge
Alyx Vance
Characters played by Mike Shapiro
G-Man
Barney Calhoun
Characters played by Harry S. Robins
Dr. Isaac Kleiner
Characters played by Jim French
Father Grigori
Characters played by John Patrick Lowrie
Citizens
Misc. characters
Characters played by Mary Kae Irvin
Citizens
Misc. characters
Characters played by Ellen McLain
Overwatch
Characters played by Daniel Alexander
Additional Voices
Characters played by Olegar Fedoro
G-Man
in Russian edition
Characters played by Kathy Levin
HEV Suit
Characters played by Natasha Radski
HEV Suit
In Russian edition