Characters played by Carlos Alazraqui
Winslow
Lube
Characters played by Maria Bamford
Shriek Dubois
Characters played by Jim Cummings
Cat
Characters played by Nika Futterman
Lola
Characters played by Tom Kenny
Dog
Cliff
Characters played by Jane Krakowski
CatDog's Mother
Pussycat Catfield
Characters played by Dwight Schultz
Eddie
Characters played by Billy Bob Thornton
Hound Dog McDog
CatDog's Step-father
Characters played by Frank Welker
Bessie the Sea Monster
Characters played by Billy West
Rancid Rabbit