Characters played by Dave Avellone
Narrator (segment "Robin")
Narrator
Characters played by Keith Alcorn
(segment "Nanna & Lil' Puss Puss")
(segment "Fast Driver")
Characters played by Paul Claerhout
(segment "Nanna & Lil' Puss Puss")
(segment "Fast Driver")
Characters played by Ted Minoff
(segment "Science Facts!")
Telemarketer (segment "Science Facts!")
The Angry Truck Driver (segment "Broccoli's Taxicab Confessions")
Characters played by Mills Lane
(segment "Celebrity Deathmatch")
Characters played by Matt Harrigan
(segment "Ultracity 6060")
Characters played by Maurice Schlafer
(segment "Celebrity Deathmatch")
Characters played by Len Maxwell
(segment "Celebrity Deathmatch")
Characters played by Greg Pair
(segment "Science Facts!")
Bouncer (segment "Science Facts!")
Characters played by Dan Farmer
(segment "Espresso Depresso")
(segment "Open Mic Fright")
Characters played by Ross Cobin
Broccoli (segment "Broccoli's Taxicab Confessions")
Broccoli (segment "Science Facts")
Characters played by Brian Stack
Water Conditioner Guy (segment "The Coolest Water Conditioner in the World")
Weatherman (segment "Frogg's Trip to the Sun")
Characters played by John A. Davis
(segment "Nanna & Lil' Puss Puss")
Characters played by Todd Hanson
(segment "Frogg's Trip to the Sun")
Beatnik (segment "The Coolest Water Conditioner in the World")
Characters played by Matt Speigel
Frogg (segment "Frogg's Trip to the Sun")
Frogg (segment "The Coolest Water Conditioner in the World")
Characters played by Nathan Reed
(segment "Fishbar")
Characters played by Christopher Macrae
(segment "Fishbar")
Characters played by Bonnie Franklin
Bonnie Franklin (segment "Broccoli's Taxicab Confessions")
Characters played by Michael Gough
(segment "Voice B Gone")
Characters played by Nick Gibbons
(segment "Fast Driver")
Characters played by Eric S. Calderon
(segment "Ultracity 6060")
Characters played by Carlos Ramos
Italian Stereotype
NASA Nerd (segment "Day of the Monkey")
Characters played by Mike de Seve
(segment "Ultracity 6060")
Characters played by Marty McDonough
(segment "Boris the Dog")
Characters played by Corny Cole
The President (segment "Day of the Monkey")
Characters played by David McGrath
(segment "Science Facts!")
Characters played by Steven Dovas
(segment "Opposing Views")
Characters played by Peter Oedekoven
Monkey (segment "Day of the Monkey")
Characters played by Frank Ziegler
Narrator (segment "Penguins: A Documentary")
Characters played by Debbie Dunning
(segment "Fast Driver")
Characters played by Roberta Anne Swoolzner
Tara (segment "Science Facts")
Characters played by James Van Der Veen
Rip-N-Glider (segment "Rip-n-Glide")
Characters played by Jay Hathaway
(segment "Pull My Finger")
Characters played by Scott Sundholm
(segment "Fluffy")
Characters played by Karolina Kulikowski
(segment "The Untalkative Bunny")
Characters played by Rob Rock
Perry Fantabulous (segment "Science Facts")
Characters played by Mars Yotnick
(segment "Call Me Fishmael")
Characters played by Rebecca Schatzky
(segment "Boris the Dog")
Characters played by Kersten Meder
(segment "Espresso Depresso")
Characters played by Arron Rosenfeld
Science Guy (segment "Day of the Monkey")
Characters played by Scot Campbell
Narrator (segment "Rip-n-Glide")
Characters played by Romualdo Teichen
(segment "Call Me Fishmael")
Characters played by Oskar Retch
(segment "Call Me Fishmael")
Characters played by Derek Tague
(segment "Opposing Views")
Characters played by Michael Adams
Orlanda Vega (segment "Broccoli's Taxicab Confessions")
Characters played by Dan Olmsted
(segment "Pull My Finger")
Characters played by Fred Tatasciore
Screams (segment "Performance Art Starring Chainsaw Bob")
Characters played by Chris Hardwick
Screams (segment "Performance Art Starring Chainsaw Bob")
Characters played by Asif Kapadia
(segment "Pariah the Red Man")
Characters played by Mike Mitchell
Cantly
Nibbits (segment "Chunks of Life")
Characters played by Elon Gold
(segment "Celebrity Deathmatch")
Characters played by Paul Tibbitt
Ned (segment "Chunks of Life")
Characters played by Rich Hutchman
Factory Worker (segment "Frogg's Trip to the Sun")
Characters played by Ben Gruber
(segment "Ultracity 6060")
Characters played by Lisa Collins
(segment "Ultracity 6060")
Characters played by Tim Hatcher
Narrator (segment "Beat the Meatles")
Characters played by Lisa Lyons
(segment "Celebrity Deathmatch")
Characters played by Wade Sheeler
(segment "Sea Slugs")
Characters played by Robert May
(segment "Lily & Jim")
Characters played by Xeth Feinberg
(segment "The Organization")
Characters played by Merle Becker
Fly Girl (segment "Science Facts!")
Characters played by Brian Capshaw
(segment "Nanna & Lil' Puss Puss")
Characters played by Michael Bandolik
(segment "Ultracity 6060")
Characters played by Karin Anger
(segment "Lily & Jim")
Characters played by Sam Elwitt
(segment "The Organization")
Characters played by Steven Erdman
(segment "Ultracity 6060")
Characters played by John Roman
(segment "Nanna & Lil' Puss Puss")
Characters played by Jenny Walsh
TV voice (segment "Chunks of Life")
Characters played by Adam Lane
(segment "Sea Slugs")
Characters played by Chausey Leeborn
TV voice (segment "Chunks of Life")
Characters played by Mike Libonati
(segment "Sea Slugs")
Characters played by Cec Hall
(segment "Open Mic Fright")
Characters played by David Lavender
Mayfly (segment "Science Facts!")
Characters played by John Bailey
Narrator (segment "A Brief History of Cinema")
Characters played by Chris Cole
Warren (segment "Chunks of Life")
Characters played by Ed Shively
Screams (segment "Performance Art Starring Chainsaw Bob")
Characters played by Danny Antonucci
Voices
Characters played by Darick Robertson
Voices