Characters played by Glenn Close
Maeve McKay
Characters played by Madeline Brewer
Phillary
Characters played by Nakhane Touré
Jairo
Characters played by Gail Thomas
Lydie
Characters played by Ty Baumann
Braniel
Characters played by Christopher J. Hanke
Fintan
Characters played by Sarah Boatright
Meleanor
Characters played by Denis O'Hare
David (Dad)
Characters played by Patti LuPone
Aunt Ida (Sister Max)
Characters played by River L. Ramirez
Percepción
Characters played by Mari Moriarty
America
Characters played by Peter Scolari
Commanding General
Newscaster
Characters played by Kristen Sieh
Bonnie
Hashley
Characters played by Laurie Anderson
Homunculus
Characters played by Alan Mandell
Fr. Angus
Characters played by Matthew ZanFagna
Derrick (Male Student)
Todd Croy
Characters played by Bryan Weller
James
Characters played by Simone
Dr. Jaqueline Déesse
Characters played by Julio Torres
Crustie Boy
Wal-Mart Announcer
Characters played by Donnetta Lavinia Grays
Fredwina
Characters played by Stephen Payne
Jack
Characters played by James Monroe Iglehart
Ronnie Castro
Characters played by Phillip James Brannon
Lavette
Characters played by Mx Justin Vivian Bond
Professor Karen Gunt
Characters played by Stephen Winter
Christian Man
Characters played by Shalewa Sharpe
Yvette
Characters played by Matthew Piazzi
Elvis
Characters played by Kathryn Allison
Carla Bottoms
Characters played by John Cameron Mitchell
Ceann McKay (2019)
Characters played by Ben Foster
William S. Burroughs (2019)